<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mabee, Paula M.</style></author><author><style face="normal" font="default" size="100%">Arratia, Gloria F</style></author><author><style face="normal" font="default" size="100%">Coburn, Miles</style></author><author><style face="normal" font="default" size="100%">Haendel, Melissa</style></author><author><style face="normal" font="default" size="100%">Hilton, Eric J.</style></author><author><style face="normal" font="default" size="100%">Lundberg, John G.</style></author><author><style face="normal" font="default" size="100%">Mayden, Richard L.</style></author><author><style face="normal" font="default" size="100%">Rios, Nelson</style></author><author><style face="normal" font="default" size="100%">Westerfield, Monte</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Connecting evolutionary morphology to genomics using ontologies: A case study from cypriniformes including zebrafish</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Experimental Zoology</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anatomy and Histology - Gross anatomy</style></keyword><keyword><style  face="normal" font="default" size="100%">computer software Osteichthyes [85206] Computational Biology Zebrafish Information Network database Computer Applications Morphology Evolution and Adaptation Pisces Vertebrata Chordata Animalia 00530</style></keyword><keyword><style  face="normal" font="default" size="100%">documentation</style></keyword><keyword><style  face="normal" font="default" size="100%">Evolution 11102</style></keyword><keyword><style  face="normal" font="default" size="100%">General biology - Information</style></keyword><keyword><style  face="normal" font="default" size="100%">retrieval and computer applications 01500</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2007</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&amp;SrcAuth=ResearchSoft&amp;SrcApp=EndNote&amp;DestLinkType=FullRecord&amp;DestApp=BIOABS&amp;KeyUT=BACD200800015096</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">5</style></number><volume><style face="normal" font="default" size="100%">308B</style></volume><pages><style face="normal" font="default" size="100%">655-668</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;One focus of developmental biology is to understand how genes regulate development, and therefore examining the phenotypic effects of gene mutation is a major emphasis in studies of zebrafish and other model organisms. Genetic change underlies alterations in evolutionary characters, or phenotype, and morphological phylogenies inferred by comparison of these characters. We will utilize both existing and new ontologies to connect the evolutionary anatomy and image database that is being developed in the Cypriniformes Tree of Life project to the Zebrafish Information Network (HYPERLINK &amp;quot;file://localhost/Library/Local%20Settings/Temp/ zfin.org&amp;quot; zfin.org) database. Ontologies are controlled vocabularies that formally represent hierarchical relationships among defined biological concepts. If used to recode the free-form text descriptors of anatomical characters, evolutionary character data can become more easily computed, explored, and mined. A shared ontology for homologous modules of the phenotype must be referenced to connect the growing databases in each area in a way that evolutionary questions can be addressed. We present examples that demonstrate the broad utility of this approach.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><accession-num><style face="normal" font="default" size="100%">Bacd200800015096</style></accession-num><notes><style face="normal" font="default" size="100%">&lt;p&gt;Article&lt;/p&gt;</style></notes><custom1><style face="normal" font="default" size="100%">&lt;p&gt;&amp;nbsp;JT 10/28/11&lt;/p&gt;</style></custom1></record></records></xml>